
Growth Hormone
Tesamorelin (GHRH Analog)
Stabilized GHRH analog — pulsatile GH release and body composition research
Select Size
Most researchers order 2+ vials per protocol
For research use only. Not for human consumption.
Overview
Tesamorelin is a synthetic analog of human growth hormone-releasing hormone (GHRH) consisting of the full 44-amino acid GHRH(1-44) sequence with an N-terminal trans-3-hexenoic acid modification conferring enhanced enzymatic stability. It binds the GHRH receptor on pituitary somatotrophs, stimulating adenylyl cyclase activity and cAMP-mediated GH gene transcription. Tesamorelin preserves physiological GH pulsatility and is studied for its effects on growth hormone dynamics, lipid metabolism, and body composition parameters in preclinical models.
Specifications
| Form | Lyophilized Powder |
| Purity | ≥99% (HPLC Verified) |
| Storage | -20°C (Freeze Dried) |
| Molecular Weight | 5135.89 g/mol |
Frequently Asked Questions
Tesamorelin is a synthetic analog of human GHRH consisting of the full 44-amino acid GHRH(1-44) sequence with an N-terminal trans-3-hexenoic acid modification for enhanced enzymatic stability. It binds the GHRH receptor on pituitary somatotrophs, stimulating cAMP-mediated GH gene transcription.
Both are GHRH receptor agonists, but Tesamorelin is based on the full-length 44-amino acid GHRH sequence, while CJC-1295 (Mod GRF 1-29) uses only the first 29 amino acids with four substitutions for DPP-IV resistance. Tesamorelin preserves more of the native GHRH structure and signaling profile.
Tesamorelin is studied for its effects on physiological GH pulsatility, lipid metabolism parameters, and body composition changes in preclinical models. Its ability to stimulate GH release while preserving natural pulsatile patterns makes it valuable for GH-axis pharmacology research.
Tesamorelin is verified at ≥99% purity via HPLC analysis. Store at -20°C. COA with full analytical data included with every order.
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